The objectives of this course are to give background on history of science, emphasizing methodologies used to do research, use framework of these methodologies for understanding effective
lab practices and scientific communication and appreciate scientific ethics.
The objectives of this laboratory course are to develop an understanding about practical aspects of components of immune system as well as their function. Basic as well as advanced methods will be taught to detect different antigen and antibody interactions, isolation of different lymphocyte cells etc. and how they can be used in respective research work.
Immunity to infection : bacteria, viral, fungal and parasitic infections (with examples from each group); hypersensitivity: Type I-IV; autoimmunity; types of autoimmune diseases; mechanism and role of CD4+ T cells; MHC and TCR in autoimmunity; treatment of autoimmune diseases; transplantation: immunological basis of graft rejection; clinical transplantation and immunosuppressive therapy; tumor immunology: tumor antigens; immune response to tumors and tumor evasion of the immune system, cancer immunotherapy; immunodeficiency: primary immunodeficiencies, acquired or secondary immunodeficiencies, autoimmune disorder, anaphylactic shock, immunosenescence, immune exhaustion in chronic viral infection, immune tolerance, NK cells in chronic viral infection and malignancy.
On completion of this course, the students are expected to:
• Develop an understanding of the basic theory of these computational tools;
• Develop required database extraction, integration, coding for computational tools and methods necessary for all Omics;
• Create hypothesis for investigating specific contemporary biological questions, provide help to experiment with or develop appropriate tools;
• Critically analyze and interpret results of their study with respect to whole systems.
Students will present one seminar on the research article of their choice.
1. Research articles should be of reasonably high impact and not before 2019.
2. The seminar will be from the research article related to their subject of choice.
3. Evaluation is for 25 Marks which includes their presentation skills and slide preparation. Each seminar will be evaluated by one internal (12.5 marks) and one external examiner
(12.5 marks) and the marks will be accordingly assigned as internal and external marks.
4. Attendance for all M.Sc. II students is compulsory.
5. Student has to present his/her seminar on scheduled date and time only.